MARKET REACTION AND SHARE PERFORMANCE TOWARDS THE MERGER AND ACQUISITION ANNOUNCEMENT OF 2015-2019


Long-Read Metagenome-Assembled Genomes Improve Identification of Novel Complete Biosynthetic Gene Clusters in a Complex Microbial Activated Sludge Ecosystem

ABSTRACT Microorganisms produce a wide variety of secondary/specialized metabolites (SMs), the majority of which are yet to be discovered.These natural products play multiple roles in microbiomes and are important for microbial competition, communication, and success in the environment.SMs have been our major source of antibiotics and are used in a

read more



ALK upregulates POSTN and WNT signaling to drive neuroblastoma

Summary: Neuroblastoma is the most common extracranial solid tumor of childhood.While MYCN and mutant anaplastic lymphoma kinase (ALKF1174L) cooperate in tumorigenesis, how ALK contributes to tumor formation remains unclear.Here, we used a human stem cell-based model of neuroblastoma.Mis-expression of ALKF1174L and MYCN resulted in shorter latency

read more